The .22 Remington Jet (also known as .22 Jet, .22 Center Fire Magnum, or .22 CFM)^[1] is a .22 in (5.6mm) American centerfire revolver and rifle cartridge.^[1]

Developed jointly by Remington and Smith & Wesson, it was to be used in the Model 53 revolver, which first appeared late in 1961.^[1] While it traced its origins to potent wildcats such as the .224 Harvey Kay-Chuk,^[2] which ultimately derive from the .22 Hornet,^[2] it was a bottlenecked cartridge based upon the .357 Magnum case necked down to a .22 caliber bullet, with an unusually long tapered shoulder.

By 1972, the Model 53 remained the only revolver chambered for it,^[1] while Marlin in 1972 was planning a lever rifle in .22 Jet.^[1]

The .22 Jet was also a factory chambering for the T/C Contender and the design allowed for it to reach its full potential. No cylinder gap, no case setback.^{[3][circular reference]}

The .22 Jet was designed as a flat-shooting hunting round for handguns, and it is suitable for handgun hunting of varmints and medium game out to 100 yd (90 m).^[1] The 2460 ft/s (750 m/s) and 535 ft-lbf (725 J) claimed for factory test loads did not prove out in service weapons.^[1]